Fabrication of a self-assembled honeycomb nanofibrous scaffold to guide endothelial morphogenesis

Fabrication and characterization of nanofibrous tricuspid valve scaffold based on polyurethane for heart valve tissue engineering

Objective(s): Tissue engineering represents a new approach to solve the current complications of the heart valve replacements by offering viable valve prosthesis with growth and remodeling capability. In this project, electrospinning and dip coating techniques were used to fabricate heart valve constructs from medical grade polyurethane (PU). Methods: Fir...

Towards a self-assembled honeycomb structure via diaminotriptycene metal complexes.

We illustrate a new approach toward the synthesis of a porous supramolecular honeycomb based on triptycene. A coordination polymer has been prepared where the triptycene groups are linked through triptycenesemiquinonediimine platinum complexes, but the product is disordered rather than the intended honeycomb structure. A model platinum complex and its (15)N-labeled isotopomer have been prepared...

Aligning 3D nanofibrous networks from self-assembled phenylalanine nanofibers.

Self-assembled synthetic materials are typically disordered, and controlling the alignment of such materials at the nanometer scale may be important for a variety of biological applications. In this study, we have applied directional freeze-drying, for the first time, to develop well aligned three dimensional (3D) nanofibrous materials using amino acid like L-phenylalanine (Phe). 3D free-standi...

Nanofibrous scaffold in tissue engineering

Dear Friends, Nanofibrous scaffolds have been a major revolution in the field of tissue engineering which may improve the health and quality of life by enhancing tissue function. These are the artificial extracellular matrices which offer natural surroundings for tissue formation. Owing to their high surface to volume ratio, nanofibrous scaffolds increase cell adhesion, proliferation, and diffe...

Fabrication of Chitosan Based Nanofibrous Scaffold Using Free Surface Electrospinning for Tissue Engineering Application